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). In the free of charge ChVLig-AMP, the OB domain is mirrored away from the NTase domain to completely expose the DNA-binding area above the AMP-binding pocket. The peptide segment that may be destined to become the latch is disordered in the free of charge ligase and sensitive to proteolysis, but this section is protected against proteolysis when ChVLig binds to nicked DNA.
Pues bien, a la par de esta noticia hay otra buena que tiene que ver ya más con el tema de los abonos y las boletas para este semestre.
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“A través de nuestra tiquetera Entradas Millonarios se podrá realizar la compra de entradas para los partidos oficiales del equipo, así como también gestionar la compra o recarga de abonos.
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). The NTase domain binds to your damaged and intact DNA strands in the main groove flanking the nick in addition to in the minor groove to the 3′-OH facet from the nick (supplemental Fig. Ligaz Slots S3). The OB domain binds through the minimal groove to the experience of the duplex guiding the nick.
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